FORMULATION OF RED BETEL LEAF EXTRACT SERUM (Piper crocatum Ruiz & Pav.) AS ANTIOXIDANT

Red betel leaf (Piper crocatum Ruiz & Pav.) is a plant that has medicinal and cosmetic properties. One of the cosmetics used by society today facial serum. The purpose this study was formulation serum from red water extract. extract obtained means Pressurized Hot Water Extraction method using distilled as solvent, then phytochemical screening carried out. Serum made in several concentrations, namely 1.5% (F1); 2% (F2);3%;(F3) blank (F0). quality inspection preparation includes homogeneity test, pH, viscosity, stability, irritation hedonic antioxidant activity test. results contained alkaloids, flavonoids, tannins, saponins triterpenoids. formulated into homogeneous with temporary pH range 6.1-6.2 after testing 5.8-6.1 does not irritate skin. test showed included "strong" category an IC50 value 38.30 g/ml. values ​​for preparations F0, F1, F2 F3 were 430.3689 g/ml (weak), 252.03 (moderate), 115.6 (moderate) 58.13 (strong). Based on study, it concluded all formulas homogeneous, stable did skin 3% (F3) had best strong antioxidants.